Name: Caffeine Anhydrous REMARK: DESCRIPTION: Caffeine Anhydrous is A xanthine alkaloid mainly extracted from the seed of the coffee plant and the leaves of the tea bush, available as White or almost white, crystalline powder or silky, white or almost white, crystals.   SPECIFICATION:  Test Term Specification Appearance White crystalline powder Identification: IR conform to reference spectrum HPLC Conform to chromatogram of the standard preparation Melting point(℃） 234-239 Appearance of solution Should be clear,colorless Solubility Sparingly soluble in water, freely soluble in boiling water, slightly soluble in ethanol(96%). It dissolves in concentrated solutions of alkali benzoates or salicylates. It sublimes readily. Acidity(0.01mol/L NaOH, ml) ≤0.2 Chromatographic purity:single impurity ≤0.10% Total impurities ≤0.1 Sulfate ≤500ppm Heavy metal ≤0.001（on Pb basis)(%) Loss on drying ≤0.5% Residue on ignition ≤0.1% Sulphated ash ≤0.1% Residual solvent ≤60ppm Mesh size 100% pass 40 mesh Assay(on dried basis)(HPLC)

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