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Name: Aspirin



REMARK:

Aspirin, also known as acetylsalicylic acid (ASA), is a medication, often used to treat pain, fever, andinflammation. Aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clotformation in people at high risk of developing blood clots. Low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or the death of heart tissue.Aspirin may be effective at preventing certain types of cancer, particularly colorectal cancer.
Aspirin is part of a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), but differs from most other NSAIDs in the mechanism of action. The salicylates have similar effects (antipyretic, anti-inflammatory, analgesic) to the other NSAIDs and inhibit the same enzyme cyclooxygenase (COX), but aspirin does so in an irreversiblemanner and, unlike others, affects the COX-1 variant more than the COX-2 variant of the enzyme.Aspirin also has anantiplatelet effect by stopping the binding together of platelets.
 
SPECIFICATION: 
Item
Specifications
Appearance 
White crystalline powder
 or white crystals
Identification: AIR-Spectrum
Conforms 
Appearance of solution
Clear and colorless
Assay
99.5%-100.5%
Limit of free salicylic acid
≤0.1%
Loss o drying
≤0.5%
Residue on ignition
≤0.05%
Substances insolution in sodium carbonate TS
Clear
Rendily carbonlznble 
≤Matching fluid Q
Substances
≤0.04%
Sulphate
≤0.001%
Chloride
≤0.014%
Related substances: any single impurity
≤0.1%
Total impurities
≤0.25%
Residual solvents
LOD≤0.5%


 




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